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Co-ordinate loss of protein kinase C and multidrug resistance gene expression in revertant MCF-7/Adr breast carcinoma cells.

The aim of this study was to investigate the link between protein kinase C (PKC) and multidrug resistance (mdr) phenotype. The expression of both was studied in doxorubicin-resistant MCF-7/Adr cells as they reverted to the wild-type phenotype when cultured in the absence of drug. The following param...

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Autors principals: Budworth, J., Gant, T. W., Gescher, A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228231/
https://ncbi.nlm.nih.gov/pubmed/9155054
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