The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ in human leukaemia and colorectal carcinoma cell lines.

Thymidylate synthase (TS) expression has been characterized for a panel of eight human colorectal carcinoma and five human leukaemia cell lines, to relate differences in intrinsic TS activity, protein and mRNA levels to growth inhibition caused by continuous exposure to THYMITAQ, a specific non-clas...

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Bibliographic Details
Main Authors: Estlin, E. J., Balmanno, K., Calvert, A. H., Hall, A. G., Lunec, J., Newell, D. R., Pearson, A. D., Taylor, G. A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228199/
https://ncbi.nlm.nih.gov/pubmed/9413945
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