Overexpression of human NADPH:cytochrome c (P450) reductase confers enhanced sensitivity to both tirapazamine (SR 4233) and RSU 1069.

Lignende værker

• NADPH:cytochrome c (P450) reductase activates tirapazamine (SR4233) to restore hypoxic and oxic cytotoxicity in an aerobic resistant derivative of the A549 lung cancer cell line
  af: Saunders, M P, et al.
  Udgivet: (2000)
• Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR 4233).
  af: Patterson, A. V., et al.
  Udgivet: (1995)
• Differentially regulated NADPH:cytochrome P450 oxidoreductases in parsley
  af: Koopmann, Edda, et al.
  Udgivet: (1997)
• Does reductive metabolism predict response to tirapazamine (SR 4233) in human non-small-cell lung cancer cell lines?
  af: Chinje, E C, et al.
  Udgivet: (1999)
• Measurement of cytochrome P450 and NADPH–cytochrome P450 reductase
  af: Guengerich, F Peter, et al.
  Udgivet: (2009)