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Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain.

Progress in our understanding of the contribution of P-glycoprotein (P-gp)-mediated resistance to chemotherapy failure in haematological as well as solid tumours has been hampered by the lack of highly sensitive, reliable methods for the detection of P-gp function in fresh human tumour cells. The pr...

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Main Authors: Broxterman, H. J., Schuurhuis, G. J., Lankelma, J., Oberink, J. W., Eekman, C. A., Claessen, A. M., Hoekman, K., Poot, M., Pinedo, H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228098/
https://ncbi.nlm.nih.gov/pubmed/9376262
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