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Heterologous Expression of the Pneumococcal Serotype 14 Polysaccharide in Lactococcus lactis Requires Lactococcal epsABC Regulatory Genes

The pneumococcal serotype 14 polysaccharide was produced in Lactococcus lactis by coexpressing pneumococcal polysaccharide type 14-specific genes (cpsFGHIJKL(14)) with the lactococcal regulatory and priming glucosyltransferase-encoding genes specific for B40 polysaccharide (epsABCD(B40)). The polysa...

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Bibliographic Details
Main Authors: Nierop Groot, Masja N., Godefrooij, Jeroen, Kleerebezem, Michiel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227717/
https://ncbi.nlm.nih.gov/pubmed/18083858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01655-07
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