Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

Wiskott-Aldrich syndrome protein (WASp) is a hematopoietic-specific, multidomain protein whose mutation is responsible for the immunodeficiency disorder Wiskott-Aldrich syndrome. WASp contains a binding motif for the Rho GTPase CDC42Hs as well as verprolin/cofilin-like actin-regulatory domains, but...

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Bibliographische Detailangaben
Hauptverfasser: Linder, Stefan, Nelson, David, Weiss, Michael, Aepfelbacher, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22264/
https://ncbi.nlm.nih.gov/pubmed/10449748
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