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Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

Wiskott-Aldrich syndrome protein (WASp) is a hematopoietic-specific, multidomain protein whose mutation is responsible for the immunodeficiency disorder Wiskott-Aldrich syndrome. WASp contains a binding motif for the Rho GTPase CDC42Hs as well as verprolin/cofilin-like actin-regulatory domains, but...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Linder, Stefan, Nelson, David, Weiss, Michael, Aepfelbacher, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449748/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9648
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