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Human platelet secretion and aggregation induced by calcium ionophores. Inhibition by PGE1 and dibutyryl cyclic AMP

Ca2+, Mg2+-ionophores X537A and A23,187 (10(-7)-10(-6) M) induced the release of adenine nucleotides adenosine diphosphate (ADP, adenosine triphosphate (ATP), serotonin, beta-glucuronidase, Ca2+, and Mg2+ from washed human platelets. Enzymes present in the cytoplasm or mitochondria, and Zn2+ were no...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1975
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2226221/
https://ncbi.nlm.nih.gov/pubmed/172596
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