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LIF Removal Increases CRABPI and CRABPII Transcripts in Embryonic Stem Cells Cultured in Retinol or 4-Oxoretinol

In this manuscript we demonstrate that the combination of LIF removal and retinol or 4-oxoretinol treatment results in dose dependent, very large increases in CRABPI and CRABPII mRNA levels in embryonic stem cells. Transient transfection experiments demonstrate that the 7.8 kb CRABPI promoter does n...

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Bibliografiske detaljer
Main Authors: Lane, Michelle A., Xu, Juliana, Wilen, Elana W., Sylvester, Renia, Derguini, Fadila, Gudas., Lorraine J.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225994/
https://ncbi.nlm.nih.gov/pubmed/18006143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2007.09.010
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