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Binding of buried structural water increases the flexibility of proteins

Water deeply buried in proteins is considered to be an integral part of the folded structure. Such structural water molecules make strong H bonds with polar groups of the surrounding protein and therefore are believed to tighten the protein matrix. Surprisingly, our computational analysis of the bin...

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Detalhes bibliográficos
Main Authors: Fischer, Stefan, Verma, Chandra S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22257/
https://ncbi.nlm.nih.gov/pubmed/10449741
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