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Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome in China
Objective: To explore the relationship between genetic polymorphisms in methylenetetrahydrofolate reductase (MTHFR), methionine synthase reductase (MTRR), the central enzymes in folate metabolism that affects DNA methylation and synthesis, and the risk of Down syndrome in China. Methods: Genomic DNA...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Zhejiang University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2225490/ https://ncbi.nlm.nih.gov/pubmed/18257130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B0710599 |
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