PEROXYNITRITE IS A POTENT INHIBITOR OF NF-κ B ACTIVATION TRIGGERED BY INFLAMMATORY STIMULI IN CARDIAC AND ENDOTHELIAL CELL LINES

Peroxynitrite is a potent oxidant and nitrating species proposed as a direct effector of myocardial damage in numerous cardiac pathologies. Whether peroxynitrite also acts indirectly, by modulating cell signal transduction in the myocardium, has not been investigated. We therefore examined a possibl...

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Main Authors: Levrand, Sandra, Pesse, Benoît, Feihl, François, Waeber, Bernard, Pacher, Pal, Rolli, Joëlle, Schaller, Marie-Denise, Liaudet, Lucas
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225482/
https://ncbi.nlm.nih.gov/pubmed/16079150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M501977200
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