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Cloning, expression, purification, crystallization and preliminary crystallographic analysis of pseudo death-effector domain of HIPPI, a molecular partner of Huntingtin-interacting protein HIP-1

The formation of a heterodimer between Huntingtin-interacting protein-1 (HIP-­1) and its novel partner HIPPI (HIP-1 protein interactor) through their pseudo death-effector domains (pDEDs) is a key step that recruits caspase-8 and initiates apoptosis. This could be one of the pathways by which apopto...

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Hlavní autoři: Banerjee, Manisha, Majumder, Pritha, Bhattacharyya, Nitai P., Dattagupta, Jiban K., Sen, Udayaditya
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225382/
https://ncbi.nlm.nih.gov/pubmed/17142908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106046628
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