Intranasal Granulocyte-Macrophage Colony-Stimulating Factor Reduces the Aspergillus Burden in an Immunosuppressed Murine Model of Pulmonary Aspergillosis

We demonstrated that intranasal granulocyte-macrophage colony-stimulating factor given to immunosuppressed mice infected with pulmonary aspergillosis resulted in a sixfold reduction in the lung fungal burden compared to the result for saline-treated mice (P = 0.045). These data suggest that lung-tar...

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Bibliographische Detailangaben
Hauptverfasser: Quezada, Gerardo, Koshkina, Nadezhda V., Zweidler-McKay, Patrick, Zhou, Zichao, Kontoyiannis, Dimitrios P., Kleinerman, Eugenie S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Biologic Response Modifiers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224773/
https://ncbi.nlm.nih.gov/pubmed/17984233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00760-07
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