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Novel Plant Virus-Based Vaccine Induces Protective Cytotoxic T-Lymphocyte-Mediated Antiviral Immunity through Dendritic Cell Maturation

Currently used vaccines protect mainly through the production of neutralizing antibodies. However, antibodies confer little or no protection for a majority of chronic viral infections that require active involvement of cytotoxic T lymphocytes (CTLs). Virus-like particles (VLPs) have been shown to be...

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Detalles Bibliográficos
Main Authors: Lacasse, Patrick, Denis, Jérôme, Lapointe, Réjean, Leclerc, Denis, Lamarre, Alain
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224570/
https://ncbi.nlm.nih.gov/pubmed/17989184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01811-07
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