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Amiloride Derivatives Inhibit Coxsackievirus B3 RNA Replication

Amiloride derivatives are known blockers of the cellular Na(+)/H(+) exchanger and the epithelial Na(+) channel. More recent studies demonstrate that they also inhibit ion channels formed by a number of viral proteins. We previously reported that 5-(N-ethyl-N-isopropyl)amiloride (EIPA) modestly inhib...

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Autors principals: Harrison, David N., Gazina, Elena V., Purcell, Damian F., Anderson, David A., Petrou, Steven
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224459/
https://ncbi.nlm.nih.gov/pubmed/18032495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01374-07
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