JC Virus Agnoprotein Inhibits In Vitro Differentiation of Oligodendrocytes and Promotes Apoptosis

Productive infection of oligodendrocytes, which are responsible for the formation of myelin sheath in the central nervous system, with the human neurotropic virus JC virus (JCV) causes the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML). In addition to encoding T antigen...

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Bibliographic Details
Main Authors: Merabova, Nana, Kaniowska, Dorota, Kaminski, Rafal, Deshmane, Satish L., White, Martyn K., Amini, Shohreh, Darbinyan, Armine, Khalili, Kamel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224429/
https://ncbi.nlm.nih.gov/pubmed/17989177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01680-07
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