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Protective role of Purα to cisplatin

BACKGROUND: The nucleic acid-binding protein Purα is involved at stalled DNA replication forks, in double-strand break (DSB) DNA repair and the cellular response to DNA replication stress. Purα also regulates homologous recombination-directed DNA repair (HRR). RESULTS: Cells lacking Purα showed enha...

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Autors principals: Kaminski, Rafal, Darbinyan, Armine, Merabova, Nana, Deshmane, Satish L., White, Martyn K., Khalili, Kamel
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670774/
https://ncbi.nlm.nih.gov/pubmed/18927497
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