Calpain 1 and 2 Are Required for RNA Replication of Echovirus 1

Calpains are calcium-dependent cysteine proteases that degrade cytoskeletal and cytoplasmic proteins. We have studied the role of calpains in the life cycle of human echovirus 1 (EV1). The calpain inhibitors, including calpeptin, calpain inhibitor 1, and calpain inhibitor 2 as well as calpain 1 and...

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Bibliografski detalji
Glavni autori: Upla, Paula, Marjomäki, Varpu, Nissinen, Liisa, Nylund, Camilla, Waris, Matti, Hyypiä, Timo, Heino, Jyrki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Virus-Cell Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224425/
https://ncbi.nlm.nih.gov/pubmed/18032503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01375-07
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