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Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins

Receptor-promoted GTP binding and GTPase-activating protein (GAP)-promoted GTP hydrolysis determine the onset and termination of G protein signaling; they coordinately control signal amplitude. The mechanisms whereby cells independently regulate signal kinetics and signal amplitude are therefore cen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Mukhopadhyay, Suchetana, Ross, Elliott M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22244/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449728/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9539
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