The Tyrosine Kinase sf-Stk and Its Downstream Signals Are Required for Maintenance of Friend Spleen Focus-Forming Virus-Induced Fibroblast Transformation

Infection of erythroid progenitor cells by Friend spleen focus-forming virus (SFFV) leads to acute erythroid hyperplasia and eventually to erythroleukemia in susceptible strains of mice. The viral envelope protein, SFFV gp55, forms a complex with the erythropoietin receptor (EpoR) and a short form o...

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Detalhes bibliográficos
Main Authors: Jelacic, Tanya M., Thompson, Delores, Hanson, Charlotte, Cmarik, Joan L., Nishigaki, Kazuo, Ruscetti, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224391/
https://ncbi.nlm.nih.gov/pubmed/17959667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01349-07
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