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Friend Spleen Focus-Forming Virus Activates the Tyrosine Kinase sf-Stk and the Transcription Factor PU.1 to Cause a Multi-Stage Erythroleukemia in Mice

Hematological malignancies in humans typically involve two types of genetic changes: those that promote hematopoietic cell proliferation and survival (often the result of activation of tyrosine kinases) and those that impair hematopoietic cell differentiation (often the result of changes in transcri...

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Detalhes bibliográficos
Main Authors: Cmarik, Joan, Ruscetti, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185572/
https://ncbi.nlm.nih.gov/pubmed/21994618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2102235
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