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Kaposi's Sarcoma-Associated Herpesvirus K-Cyclin Interacts with Cdk9 and Stimulates Cdk9-Mediated Phosphorylation of p53 Tumor Suppressor

K-cyclin, encoded by Kaposi's sarcoma-associated herpesvirus, has previously been demonstrated to activate cyclin-dependent kinase 6 (Cdk6) to induce the phosphorylation of various cell cycle regulators. In this study, we identified Cdk9 as a new K-cyclin-associated Cdk and showed that K-cyclin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chang, Pei-Ching, Li, Mengtao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224387/
https://ncbi.nlm.nih.gov/pubmed/17942552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01552-07
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