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The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastoma protein and histone H1.

Kaposi's sarcoma-associated herpesvirus (KSHV or human herpesvirus 8) is a novel gammaherpesvirus implicated in the cause of Kaposi's sarcoma and certain malignancies of lymphatic origin. One of the candidate genes possibly involved in promoting tumor development is an open reading frame (ORF) with...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Godden-Kent, D, Talbot, S J, Boshoff, C, Chang, Y, Moore, P, Weiss, R A, Mittnacht, S
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151805/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4193-4198.1997
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