Different Abilities of Escape Mutant-Specific Cytotoxic T Cells To Suppress Replication of Escape Mutant and Wild-Type Human Immunodeficiency Virus Type 1 in New Hosts

There is much evidence that in human immunodeficiency virus type 1 (HIV-1)-infected individuals, strong cytotoxic T lymphocyte (CTL)-mediated immune pressure results in the selection of HIV-1 mutants that have escaped from wild-type-specific CTLs. If escape mutant-specific CTLs are not elicited in n...

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Main Authors: Fujiwara, Mamoru, Tanuma, Junko, Koizumi, Hirokazu, Kawashima, Yuka, Honda, Kazutaka, Mastuoka-Aizawa, Saori, Dohki, Sachi, Oka, Shinichi, Takiguchi, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224353/
https://ncbi.nlm.nih.gov/pubmed/17959671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01452-07
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