Structure-based design of an RNA-binding zinc finger
A structure-based approach was used to design RNA-binding zinc fingers that recognize the HIV-1 Rev response element (RRE). An arginine-rich α-helix from HIV-1 Rev was engineered into the zinc finger framework, and the designed fingers were shown to bind specifically to the RRE with high affinity an...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9521 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|