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No Genetic Bottleneck in Plasmodium falciparum Wild-Type Pfcrt Alleles Reemerging in Hainan Island, China, following High-Level Chloroquine Resistance

Chloroquine-resistant Plasmodium falciparum was highly prevalent in Hainan, China, in the 1970s. Twenty-five years after cessation of chloroquine therapy, the prevalence of P. falciparum wild-type Pfcrt alleles has risen to 36% (95% confidence interval, 22.1 to 52.4%). The diverse origins of wild-ty...

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Hlavní autoři: Chen, Nanhua, Gao, Qi, Wang, Shanqing, Wang, Guangze, Gatton, Michelle, Cheng, Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223894/
https://ncbi.nlm.nih.gov/pubmed/17954685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00711-07
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