Functional Role of the PE Domain and Immunogenicity of the Mycobacterium tuberculosis Triacylglycerol Hydrolase LipY

PE and PPE proteins appear to be important for virulence and immunopathogenicity in mycobacteria, yet the functions of the PE/PPE domains remain an enigma. To decipher the role of these domains, we have characterized the triacylglycerol (TAG) hydrolase LipY from Mycobacterium tuberculosis, which is...

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Autori principali: Mishra, Kanhu C., de Chastellier, Chantal, Narayana, Yeddula, Bifani, Pablo, Brown, Alistair K., Besra, Gurdyal S., Katoch, Vishwa M., Joshi, Beenu, Balaji, Kithiganahalli N., Kremer, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223678/
https://ncbi.nlm.nih.gov/pubmed/17938218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00410-07
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