Recombinant Holotoxoid Vaccine against Botulism

The botulinum neurotoxins (BoNT) are the most toxic proteins for humans and designated “Category A Select Agents.” The current vaccine against botulism is in limited supply, and there is a need to develop new vaccine strategies. A recombinant BoNT/A toxoid was produced in Clostridium botulinum that...

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Hlavní autoři: Pier, Christina L., Tepp, William H., Bradshaw, Marite, Johnson, Eric A., Barbieri, Joseph T., Baldwin, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223665/
https://ncbi.nlm.nih.gov/pubmed/17967862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00843-07
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