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Enhancing toxin-based vaccines against botulism
Botulinum neurotoxins (BoNT) are the most toxic proteins for humans. BoNTs are single chain proteins with an N-terminal light chain (LC) and a C-terminal heavy chain (HC). HC comprises a translocation domain (HC(N)) and a receptor binding domain (HC(C)). Currently, there are no approved vaccines aga...
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| Publicado no: | Vaccine |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5820173/ https://ncbi.nlm.nih.gov/pubmed/29307477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.12.064 |
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