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Mechanisms of Dexamethasone-Mediated Inhibition of Toll-Like Receptor Signaling Induced by Neisseria meningitidis and Streptococcus pneumoniae

Excessive inflammation contributes to the pathogenesis of bacterial meningitis, which remains a serious disease despite treatment with antibiotics. Therefore, anti-inflammatory drugs have important therapeutic potential, and clinical trials have revealed that early treatment with dexamethasone signi...

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Autori principali: Mogensen, Trine H., Berg, Randi S., Paludan, Søren R., Østergaard, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223664/
https://ncbi.nlm.nih.gov/pubmed/17938219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00856-07
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