A DNA Fusion Vaccine Induces Bactericidal Antibodies to a Peptide Epitope from the PorA Porin of Neisseria meningitidis

An experimental DNA plasmid vaccine was developed based on a well-characterized and protective peptide epitope derived from a bacterial porin protein. For this study, we used the P1.16b serosubtype epitope, located in variable region (VR)2 in loop 4 of the PorA outer membrane (OM) porin from Neisser...

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Hlavní autoři: Zhu, Delin, Williams, Jeannette N., Rice, Jason, Stevenson, Freda K., Heckels, John E., Christodoulides, Myron
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223639/
https://ncbi.nlm.nih.gov/pubmed/17967859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00943-07
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