Intranasal Interleukin-12 Therapy Inhibits Mycoplasma pneumoniae Clearance and Sustains Airway Obstruction in Murine Pneumonia

Mycoplasma pneumoniae is a leading cause of pneumonia and is associated with asthma. Evidence links M. pneumoniae respiratory disease severity with interleukin-12 (IL-12) concentrations in respiratory secretions. We evaluated the effects of IL-12 therapy on microbiologic, inflammatory, and pulmonary...

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Hlavní autoři: Salvatore, C. M., Fonseca-Aten, M., Katz-Gaynor, K., Gomez, A. M., Hardy, R. D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223484/
https://ncbi.nlm.nih.gov/pubmed/18039833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00878-07
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