Prosurvival Effect of DHCR24/Seladin-1 in Acute and Chronic Responses to Oxidative Stress

DHCR24/seladin-1, a crucial enzyme in sterol synthesis, is of lower abundance in brain areas affected by Alzheimer's disease. While high levels of DHCR24/seladin-1 exert antiapoptotic function by conferring resistance against oxidative stress, the molecular mechanism for this protective effect...

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Main Authors: Kuehnle, Katrin, Crameri, Arames, Kälin, Roland E., Luciani, Paola, Benvenuti, Susanna, Peri, Alessandro, Ratti, Francesca, Rodolfo, Monica, Kulic, Luka, Heppner, Frank L., Nitsch, Roger M., Mohajeri, M. Hasan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223428/
https://ncbi.nlm.nih.gov/pubmed/17984220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00584-07
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