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Global Role for Polyadenylation-Assisted Nuclear RNA Degradation in Posttranscriptional Gene Silencing

Fission yeast Cid14, a component of the TRAMP (Cid14/Trf4-Air1-Mtr4 polyadenylation) complex, polyadenylates nuclear RNA and stimulates degradation by the exosome for RNA quality control. Here, we analyze patterns of global gene expression in cells lacking the Cid14 or the Dis3/Rpr44 subunit of the...

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Detalhes bibliográficos
Main Authors: Wang, Shao-Win, Stevenson, Abigail L., Kearsey, Stephen E., Watt, Stephen, Bähler, Jürg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223409/
https://ncbi.nlm.nih.gov/pubmed/18025105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01531-07
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