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P-TEFb Is Critical for the Maturation of RNA Polymerase II into Productive Elongation In Vivo
Positive transcription elongation factor b (P-TEFb) is the major metazoan RNA polymerase II (Pol II) carboxyl-terminal domain (CTD) Ser2 kinase, and its activity is believed to promote productive elongation and coupled RNA processing. Here, we demonstrate that P-TEFb is critical for the transition o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2223398/ https://ncbi.nlm.nih.gov/pubmed/18070927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01859-07 |
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