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Voltage-insensitive Gating after Charge-neutralizing Mutations in the S4 Segment of Shaker Channels

Shaker channel mutants, in which the first (R362), second (R365), and fourth (R371) basic residues in the S4 segment have been neutralized, are found to pass potassium currents with voltage-insensitive kinetics when expressed in Xenopus oocytes. Single channel recordings clarify that these channels...

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Détails bibliographiques
Auteurs principaux: Bao, Hongxia, Hakeem, Atiya, Henteleff, Mark, Starkus, John G., Rayner, Martin D.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222989/
https://ncbi.nlm.nih.gov/pubmed/9874694
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