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Voltage-insensitive Gating after Charge-neutralizing Mutations in the S4 Segment of Shaker Channels

Shaker channel mutants, in which the first (R362), second (R365), and fourth (R371) basic residues in the S4 segment have been neutralized, are found to pass potassium currents with voltage-insensitive kinetics when expressed in Xenopus oocytes. Single channel recordings clarify that these channels...

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Bibliografske podrobnosti
Main Authors: Bao, Hongxia, Hakeem, Atiya, Henteleff, Mark, Starkus, John G., Rayner, Martin D.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222989/
https://ncbi.nlm.nih.gov/pubmed/9874694
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