GATA3-Driven Th2 Responses Inhibit TGF-β1–Induced FOXP3 Expression and the Formation of Regulatory T Cells

Transcription factors act in concert to induce lineage commitment towards Th1, Th2, or T regulatory (T(reg)) cells, and their counter-regulatory mechanisms were shown to be critical for polarization between Th1 and Th2 phenotypes. FOXP3 is an essential transcription factor for natural, thymus-derive...

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Detalhes bibliográficos
Main Authors: Mantel, Pierre-Yves, Kuipers, Harmjan, Boyman, Onur, Rhyner, Claudio, Ouaked, Nadia, Rückert, Beate, Karagiannidis, Christian, Lambrecht, Bart N, Hendriks, Rudolf W, Crameri, Reto, Akdis, Cezmi A, Blaser, Kurt, Schmidt-Weber, Carsten B
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222968/
https://ncbi.nlm.nih.gov/pubmed/18162042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050329
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