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Mutations in the S4 Region Isolate the Final Voltage-dependent Cooperative Step in Potassium Channel Activation

Charged residues in the S4 transmembrane segment play a key role in determining the sensitivity of voltage-gated ion channels to changes in voltage across the cell membrane. However, cooperative interactions between subunits also affect the voltage dependence of channel opening, and these interactio...

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Bibliografiske detaljer
Main Authors: Ledwell, Jennifer L., Aldrich, Richard W.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222902/
https://ncbi.nlm.nih.gov/pubmed/10051516
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