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Uncharged S4 Residues and Cooperativity in Voltage-dependent Potassium Channel Activation

Substitution of the S4 of Shaw into Shaker alters cooperativity in channel activation by slowing a cooperative transition late in the activation pathway. To determine the amino acids responsible for the functional changes in Shaw S4, we created several mutants by substituting amino acids from Shaw S...

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Bibliografiske detaljer
Main Authors: Smith-Maxwell, Catherine J., Ledwell, Jennifer L., Aldrich, Richard W.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217114/
https://ncbi.nlm.nih.gov/pubmed/9482709
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