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Efficient molecular docking of NMR structures: Application to HIV-1 protease

Docking ligands into an ensemble of NMR conformers is essential to structure-based drug discovery if only NMR structures are available for the target. However, sequentially docking ligands into each NMR conformer through standard single-receptor-structure docking, referred to as sequential docking,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Sheng-You, Zou, Xiaoqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222846/
https://ncbi.nlm.nih.gov/pubmed/17123961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062501507
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