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Application of NMR and Molecular Docking in Structure-based Drug Discovery

Drug discovery is a complex and costly endeavor, where few drugs that reach the clinical testing phase make it to market. High-throughput screening (HTS) is the primary method used by the pharmaceutical industry to identify initial lead compounds. Unfortunately, HTS has a high failure rate and is no...

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Publicat a:Top Curr Chem
Autors principals: Stark, Jaime L., Powers, Robert
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628936/
https://ncbi.nlm.nih.gov/pubmed/21915777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/128_2011_213
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