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Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: Crystal structures and mutation studies of bovine neurophysin-I

Current evidence indicates that the ligand-facilitated dimerization of neurophysin is mediated in part by dimerization-induced changes at the hormone binding site of the unliganded state that increase ligand affinity. To elucidate other contributory factors, we investigated the potential role of neu...

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Detalhes bibliográficos
Main Authors: Li, Xintian, Lee, Hunjoong, Wu, Jin, Breslow, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222833/
https://ncbi.nlm.nih.gov/pubmed/17192588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062444807
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