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Carboxypeptidase displaying differential velocity in hydrolysis of methotrexate, 5-methyltetrahydrofolic acid, and leucovorin.

An enzyme that catalyzes the hydrolysis of folic acid and the antifolate methotrexate nearly 20 times more rapidly than the hydrolysis of 5-methyltetrahydrofolate was extraced from a gram-negative bacterium tentatively identified as a Flavobacterium sp. The enzyme was purified 500-fold and found to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Albrecht, A M, Boldizsar, E, Hutchison, D J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1978
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC222280/
https://ncbi.nlm.nih.gov/pubmed/26657
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