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Effects of leucovorin (folinic acid) in the methotrexate-treated rat brain
Folinic acid (FA) is generally administered to patients with CNS tumors in order to treat severe neurological disorders caused by methotrexate (MTX); therefore, we herein examined the effects of the co-administration of FA on MTX concentrations in the rat brain and cerebrospinal fluid (CSF) as well...
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| Publicado en: | J Vet Med Sci |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Japanese Society of Veterinary Science
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5989019/ https://ncbi.nlm.nih.gov/pubmed/29607891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.17-0666 |
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