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Ion Channel Selectivity through Stepwise Changes in Binding Affinity
Voltage-gated Ca(2+) channels select Ca(2+) over competing, more abundant ions by means of a high affinity binding site in the pore. The maximum off rate from this site is ∼1,000× slower than observed Ca(2+) current. Various theories that explain how high Ca(2+) current can pass through such a stick...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2222772/ https://ncbi.nlm.nih.gov/pubmed/9450938 |
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