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Structure of the MecI repressor from Staphylococcus aureus in complex with the cognate DNA operator of mec
The dimeric repressor MecI regulates the mecA gene that encodes the penicillin-binding protein PBP-2a in methicillin-resistant Staphylococcus aureus (MRSA). MecI is similar to BlaI, the repressor for the blaZ gene of β-lactamase. MecI and BlaI can bind to both operator DNA sequences. The crystal str...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2222568/ https://ncbi.nlm.nih.gov/pubmed/16582476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106009742 |
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