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Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption

Osteopontin is one of the major noncollagenous bone matrix proteins produced by osteoblasts and osteoclasts, bone cells that are uniquely responsible for the remodeling of mineralized tissues. Osteoclasts express the αvβ3 integrin, which is one of the receptors for osteopontin. Recent knockout studi...

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Autores principales: Yoshitake, Hiroyuki, Rittling, Susan R., Denhardt, David T., Noda, Masaki
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC22204/
https://ncbi.nlm.nih.gov/pubmed/10393964
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