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Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation

We employed a novel mouse line that expresses low levels of human tissue factor (TF) in the absence of murine TF to analyze the role of TF in gestation. Low-TF female mice had a 14–18% incidence of fatal postpartum uterine hemorrhage, suggesting that TF plays an important role in uterine hemostasis....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Erlich, Jonathan, Parry, Graham C. N., Fearns, Colleen, Muller, Martin, Carmeliet, Peter, Luther, Thomas, Mackman, Nigel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22201/
https://ncbi.nlm.nih.gov/pubmed/10393961
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